Difference between revisions of "SpoIIP"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[SigE regulon]]}},
 
{{SubtiWiki regulon|[[SigE regulon]]}},
{{SubtiWiki regulon|[[SigF regulon]]}}
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{{SubtiWiki regulon|[[SigF regulon]]}},
 +
[[Efp-dependent proteins]]
  
 
=The gene=
 
=The gene=
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** [[SpoIID]]-[[SpoIIP]] {{PubMed|20159959}}, [[SpoIIP]]-[[SpoIIM]]  {{PubMed|17376078}}
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** [[SpoIID]]-[[SpoIIP]] {{PubMed|20159959}}
 +
** [[SpoIIP]]-[[SpoIIM]]  {{PubMed|17376078}}
  
 
* '''[[Localization]]:''' cell membrane {{PubMed|20159959}}
 
* '''[[Localization]]:''' cell membrane {{PubMed|20159959}}
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIP_2633237_2634442_-1 spoIIP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIP_2633237_2634442_-1 spoIIP] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
 
** ''[[spoIIP]]'': [[SigE]] {{PubMed|7836306}}
 
** ''[[spoIIP]]'': [[SigE]] {{PubMed|7836306}}
 
** ''[[gpr]]'':[[SigF]] {{PubMed|16497325}}
 
** ''[[gpr]]'':[[SigF]] {{PubMed|16497325}}
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* '''Additional information:'''
 
* '''Additional information:'''
 +
** [[translation]] is likely to require [[Efp]] due to the presence of several consecutive proline residues {{PubMed|23239624,23239623}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 19:22, 29 April 2013

  • Description: cell wall hydrolase with both amidase and endopeptidase activities, required for dissolution of the septal cell wall

Gene name spoIIP
Synonyms
Essential no
Product cell wall hydrolase
Function dissolution of the septal cell wall
Gene expression levels in SubtiExpress: spoIIP
Interactions involving this protein in SubtInteract: SpoIIP
MW, pI 44 kDa, 6.852
Gene length, protein length 1203 bp, 401 aa
Immediate neighbours yqxA, gpr
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoIIP expression.png















Categories containing this gene/protein

cell wall/ other, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon, SigF regulon, Efp-dependent proteins

The gene

Basic information

  • Locus tag: BSU25530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: removes the stem peptides from the cell wall and cleaves the cross-links between them PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: activity is stimulated by interaction with SpoIID PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References