Spo0M

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  • Description: sporulation-control gene

Gene name spo0M
Synonyms ygaI
Essential no
Product unknown
Function sporulation
Gene expression levels in SubtiExpress: spo0M
MW, pI 29 kDa, 4.284
Gene length, protein length 774 bp, 258 aa
Immediate neighbours trnD-Leu2, ygzA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Spo0M context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Spo0M expression.png
























Categories containing this gene/protein

sporulation/ other, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigH regulon, SigW regulon

The gene

Basic information

  • Locus tag: BSU08760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: spo0M family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • the protein is degraded by the FtsH metalloprotease PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the protein is degraded by the FtsH metalloprotease PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hue Bach Thi Nguyen, Wolfgang Schumann
The sporulation control gene spo0M of Bacillus subtilis is a target of the FtsH metalloprotease.
Res Microbiol: 2012, 163(2);114-8
[PubMed:22142536] [WorldCat.org] [DOI] (I p)

Min Cao, Phil A Kobel, Maud M Morshedi, Ming Fang Winston Wu, Chris Paddon, John D Helmann
Defining the Bacillus subtilis sigma(W) regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches.
J Mol Biol: 2002, 316(3);443-57
[PubMed:11866510] [WorldCat.org] [DOI] (P p)

W D Han, S Kawamoto, Y Hosoya, M Fujita, Y Sadaie, K Suzuki, Y Ohashi, F Kawamura, K Ochi
A novel sporulation-control gene (spo0M) of Bacillus subtilis with a sigmaH-regulated promoter.
Gene: 1998, 217(1-2);31-40
[PubMed:9795118] [WorldCat.org] [DOI] (P p)