SpmB

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  • Description: spore maturation protein (spore core dehydratation)

Gene name spmB
Synonyms ypuK
Essential no
Product spore maturation protein (spore core dehydratation)
Function germination
Gene expression levels in SubtiExpress: spmB
MW, pI 18 kDa, 5.496
Gene length, protein length 537 bp, 179 aa
Immediate neighbours rluB, spmA
Sequences Protein DNA DNA_with_flanks
Genetic context
SpmB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpmB expression.png
























Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU23170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: spmB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

D L Popham, B Illades-Aguiar, P Setlow
The Bacillus subtilis dacB gene, encoding penicillin-binding protein 5*, is part of a three-gene operon required for proper spore cortex synthesis and spore core dehydration.
J Bacteriol: 1995, 177(16);4721-9
[PubMed:7642500] [WorldCat.org] [DOI] (P p)

E B Simpson, T W Hancock, C E Buchanan
Transcriptional control of dacB, which encodes a major sporulation-specific penicillin-binding protein.
J Bacteriol: 1994, 176(24);7767-9
[PubMed:7528199] [WorldCat.org] [DOI] (P p)