Difference between revisions of "SplA"

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|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator
 
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the spl operon
+
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[splA]]-[[splB]]'' operon
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.419   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.419   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[splA]]-[[splB]]'' {{PubMed|8021181}}
  
* '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190}}
+
* '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,8021181}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** negative autoregulation by [[SplA]] {{PubMed|8021181}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
 
+
<pubmed> 15699190,8021181</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:04, 5 October 2009

  • Description: transcriptional negative regulator of the spore photoproduct lyase operon

Gene name splA
Synonyms ykxI
Essential no
Product transcriptional regulator
Function regulation of the splA-splB operon
MW, pI 9 kDa, 4.419
Gene length, protein length 237 bp, 79 aa
Immediate neighbours ptsI, splB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SplA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU13920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

M Pedraza-Reyes, F Gutiérrez-Corona, W L Nicholson
Temporal regulation and forespore-specific expression of the spore photoproduct lyase gene by sigma-G RNA polymerase during Bacillus subtilis sporulation.
J Bacteriol: 1994, 176(13);3983-91
[PubMed:8021181] [WorldCat.org] [DOI] (P p)