SpeE

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  • Description: spermidine synthase

Gene name speE
Synonyms ywhF
Essential no
Product spermidine synthase
Function spermidine, polyamine biosynthesis
Gene expression levels in SubtiExpress: speE
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 31 kDa, 5.068
Gene length, protein length 828 bp, 276 aa
Immediate neighbours speB, pbpG
Sequences Protein DNA DNA_with_flanks
Genetic context
SpeE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpeE expression.png




























Categories containing this gene/protein

miscellaneous metabolic pathways

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine (according to Swiss-Prot)
  • Protein family: spermidine/spermine synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

A Sekowska, P Bertin, A Danchin
Characterization of polyamine synthesis pathway in Bacillus subtilis 168.
Mol Microbiol: 1998, 29(3);851-8
[PubMed:9723923] [WorldCat.org] [DOI] (P p)