SndA

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  • Description: unknown

Gene name ytnL
Synonyms hipO
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ytnL
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 45 kDa, 5.545
Gene length, protein length 1248 bp, 416 aa
Immediate neighbours ytnM, ribR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtnL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtnL expression.png















Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

CymR regulon, YtlI regulon, Efp-dependent proteins

The gene

Basic information

  • Locus tag: BSU29290

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M20 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

The gene was annotated in KEGG and MetaCyc as hippurate hydrolase EC 3.5.1.32. In Swiss-Prot it is marked as “uncharacterized hydrolase”. No literature/experimental evidence supporting ththeannotation was removed as of November 2009. PubMed

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Pierre Burguière, Juliette Fert, Isabelle Guillouard, Sandrine Auger, Antoine Danchin, Isabelle Martin-Verstraete
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism.
J Bacteriol: 2005, 187(17);6019-30
[PubMed:16109943] [WorldCat.org] [DOI] (P p)

Irina M Solovieva, Rimma A Kreneva, Lubov Errais Lopes, Daniel A Perumov
The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product.
FEMS Microbiol Lett: 2005, 243(1);51-8
[PubMed:15668000] [WorldCat.org] [DOI] (P p)