SmiA

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  • Description: adaptor protein for LonA-mediated degradation of SwrA,inhibitor of swarming motility

Gene name smiA
Synonyms yvzG
Essential no
Product adaptor protein for LonA-mediated degradation of SwrA
Function control of swarming motility
Gene expression levels in SubtiExpress: smiA
MW, pI 15 kDa, 4.673
Gene length, protein length 375 bp, 125 aa
Immediate neighbours yvyD, fliT
Gene sequence (+200bp) Protein sequence
Genetic context
File:YvzG context.gif
Expression at a glance   PubMed
SmiA expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35319

Phenotypes of a mutant

A mutation in smiA suppresses the motility defect of a lytC mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage

Your additional remarks

References

Sampriti Mukherjee, Anna C Bree, Jing Liu, Joyce E Patrick, Peter Chien, Daniel B Kearns
Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation.
Proc Natl Acad Sci U S A: 2015, 112(1);250-5
[PubMed:25538299] [WorldCat.org] [DOI] (I p)

Rui Chen, Sarah B Guttenplan, Kris M Blair, Daniel B Kearns
Role of the sigmaD-dependent autolysins in Bacillus subtilis population heterogeneity.
J Bacteriol: 2009, 191(18);5775-84
[PubMed:19542270] [WorldCat.org] [DOI] (I p)