Difference between revisions of "SmiA"
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| − | * '''Description:''' inhibitor of swarming motility <br/><br/> | + | * '''Description:''' adaptor protein for [[LonA]]-mediated degradation of [[SwrA]],inhibitor of swarming motility <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || adaptor protein for [[LonA]]-mediated degradation of [[SwrA]] |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of swarming | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of swarming motility |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35319 smiA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35319 smiA] | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[LonA]]-[[SmiA]] {{PubMed|25538299}} | ||
| + | ** [[SmiA]]-[[SwrA]] (degradation) {{PubMed|25538299}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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=References= | =References= | ||
| − | <pubmed>19542270 ,, </pubmed> | + | <pubmed>19542270 ,25538299, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:18, 2 January 2015
| Gene name | smiA |
| Synonyms | yvzG |
| Essential | no |
| Product | adaptor protein for LonA-mediated degradation of SwrA |
| Function | control of swarming motility |
| Gene expression levels in SubtiExpress: smiA | |
| MW, pI | 15 kDa, 4.673 |
| Gene length, protein length | 375 bp, 125 aa |
| Immediate neighbours | yvyD, fliT |
| Gene sequence (+200bp) | Protein sequence |
| Genetic context File:YvzG context.gif | |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35319
Phenotypes of a mutant
A mutation in smiA suppresses the motility defect of a lytC mutant PubMed
Database entries
- BsubCyc: BSU35319
- DBTBS entry: no entry
- SubtiList entry: no entry
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU35319
- Structure:
- UniProt: C0H3R9
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in the Daniel Kearns lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Daniel Kearns, Indiana University, Bloomington, USA, homepage
Your additional remarks
References
Sampriti Mukherjee, Anna C Bree, Jing Liu, Joyce E Patrick, Peter Chien, Daniel B Kearns
Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation.
Proc Natl Acad Sci U S A: 2015, 112(1);250-5
[PubMed:25538299]
[WorldCat.org]
[DOI]
(I p)
Rui Chen, Sarah B Guttenplan, Kris M Blair, Daniel B Kearns
Role of the sigmaD-dependent autolysins in Bacillus subtilis population heterogeneity.
J Bacteriol: 2009, 191(18);5775-84
[PubMed:19542270]
[WorldCat.org]
[DOI]
(I p)
