Difference between revisions of "SknR"
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' yqaE'' | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' yqaE'' | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || | + | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|20889742}} |
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|style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
* essential in the wild type background (due to overexpression of the toxic proteins [[YqaH]] and [[YqaM]]) {{PubMed|20889742}} | * essential in the wild type background (due to overexpression of the toxic proteins [[YqaH]] and [[YqaM]]) {{PubMed|20889742}} | ||
| − | * no phenotype if deleted with the complete skin element {{PubMed|20889742}} | + | * no phenotype if deleted with the complete [[skin element]] {{PubMed|20889742}} |
=== Database entries === | === Database entries === | ||
Revision as of 20:12, 19 August 2012
- Description: transcription repressor of the yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqaN operon of the skin element (Xre family)
| Gene name | sknR |
| Synonyms | yqaE |
| Essential | yes PubMed |
| Product | transcription repressor |
| Function | control of prophage gene expression |
| Gene expression levels in SubtiExpress: sknR | |
| MW, pI | 13 kDa, 5.42 |
| Gene length, protein length | 348 bp, 116 aa |
| Immediate neighbours | yqaF, yqaD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
- 1 Categories containing this gene/protein
- 2 This gene is a member of the following regulons
- 3 The SknR regulon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN
- 4 The gene
- 5 The protein
- 6 Expression and regulation
- 7 Biological materials
- 8 Labs working on this gene/protein
- 9 Your additional remarks
- 10 References
Categories containing this gene/protein
transcription factors and their control, Skin element, essential genes
This gene is a member of the following regulons
The SknR regulon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN
The gene
Basic information
- Locus tag: BSU26350
Phenotypes of a mutant
- essential in the wild type background (due to overexpression of the toxic proteins YqaH and YqaM) PubMed
- no phenotype if deleted with the complete skin element PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds the yqaF promoter region to repress transcription of the yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN operon PubMed
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P45902
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742]
[WorldCat.org]
[DOI]
(I p)
