Difference between revisions of "SkfE"

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{{SubtiWiki category|[[ABC transporters]]}},
 
{{SubtiWiki category|[[ABC transporters]]}},
 
{{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}},
 
{{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}},
{{SubtiWiki category|[[membrane proteins]]}}
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{{SubtiWiki category|[[membrane proteins]]}},
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{{SubtiWiki category|[[prophage 1]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=skfE_216913_217632_1 skfE] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=skfE_216913_217632_1 skfE] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16452424 PubMed]
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16452424 PubMed]
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 11:29, 11 September 2013

  • Description: ABC transporter (binding protein), export of the spore killing factor

Gene name skfE
Synonyms ybdA
Essential no
Product ABC transporter (binding protein)
Function export of the spore killing factor SkfA
Gene expression levels in SubtiExpress: skfE
Interactions involving this protein in SubtInteract: SkfE
MW, pI 26 kDa, 6.34
Gene length, protein length 717 bp, 239 aa
Immediate neighbours skfC, skfF
Sequences Protein DNA DNA_with_flanks
Genetic context
YbdA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SkfE expression.png















Categories containing this gene/protein

ABC transporters, toxins, antitoxins and immunity against toxins, membrane proteins, prophage 1

This gene is a member of the following regulons

AbrB regulon, PhoP regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU01950

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
    • induced by phosphate starvation (PhoP) PubMed
  • Additional information: Northern blotting during during phosphate limitation showed an intense 0.25 kb skfA-specific transcript, and a weaker 6.5 kb skfA-skfB-skfC-skfE-skfF-skfG-skfH transcript. PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)

Original Publications