Difference between revisions of "SigD regulon"

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= Comments =
 
= Comments =
** the [[SigD]] regulon is strongly overexpressed in a ''[[ymdB]]'' mutant (loss of bistable gene expression) {{PubMed|21856853}}
+
* the [[SigD]] regulon is strongly overexpressed in a ''[[ymdB]]'' mutant (loss of bistable gene expression) {{PubMed|21856853}}
** expression of the [[SigD]] regulon is reduced upon overexpression of [[SlrA]], this can be suppressed by mutations in ''[[remA]]'', ''[[remB]]'', ''[[sinR]]'', or ''[[slrR]]'' {{PubMed|22329926}}
+
* expression of the [[SigD]] regulon is reduced upon overexpression of [[SlrA]], this can be suppressed by mutations in ''[[remA]]'', ''[[remB]]'', ''[[sinR]]'', or ''[[slrR]]'' {{PubMed|22329926}}
** ** expression of the [[SigD]] regulon is reduced in pnpA mutants due to reduced ''[[sigD]]'' expression {{PubMed|25099370}}
+
* expression of the [[SigD]] regulon is reduced in pnpA mutants due to reduced ''[[sigD]]'' expression {{PubMed|25099370}}
  
 
= Important publications on the [[SigD]] [[regulon]] =
 
= Important publications on the [[SigD]] [[regulon]] =

Revision as of 14:21, 19 August 2014

Regulator

SigD

Genes in this regulon

Comments

  • the SigD regulon is strongly overexpressed in a ymdB mutant (loss of bistable gene expression) PubMed
  • expression of the SigD regulon is reduced upon overexpression of SlrA, this can be suppressed by mutations in remA, remB, sinR, or slrR PubMed
  • expression of the SigD regulon is reduced in pnpA mutants due to reduced sigD expression PubMed

Important publications on the SigD regulon

Loralyn M Cozy, Andrew M Phillips, Rebecca A Calvo, Ashley R Bate, Yi-Huang Hsueh, Richard Bonneau, Patrick Eichenberger, Daniel B Kearns
SlrA/SinR/SlrR inhibits motility gene expression upstream of a hypersensitive and hysteretic switch at the level of σ(D) in Bacillus subtilis.
Mol Microbiol: 2012, 83(6);1210-28
[PubMed:22329926] [WorldCat.org] [DOI] (I p)

Christine Diethmaier, Nico Pietack, Katrin Gunka, Christoph Wrede, Martin Lehnik-Habrink, Christina Herzberg, Sebastian Hübner, Jörg Stülke
A novel factor controlling bistability in Bacillus subtilis: the YmdB protein affects flagellin expression and biofilm formation.
J Bacteriol: 2011, 193(21);5997-6007
[PubMed:21856853] [WorldCat.org] [DOI] (I p)

Masakuni Serizawa, Hiroki Yamamoto, Hirotake Yamaguchi, Yasutaro Fujita, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Systematic analysis of SigD-regulated genes in Bacillus subtilis by DNA microarray and Northern blotting analyses.
Gene: 2004, 329;125-36
[PubMed:15033535] [WorldCat.org] [DOI] (P p)

L M Márquez, J D Helmann, E Ferrari, H M Parker, G W Ordal, M J Chamberlin
Studies of sigma D-dependent functions in Bacillus subtilis.
J Bacteriol: 1990, 172(6);3435-43
[PubMed:2111808] [WorldCat.org] [DOI] (P p)


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