sigA

168

[wiki|RNA polymerase] major [wiki|sigma factor] SigA

locus: BSU_25200

Molecular weight: 42.80 kDa

pI: 4.63

Protein length: 371 aa

Gene length: 1116 bp

function: transcription

product: [wiki|RNA polymerase] major [wiki|sigma factor] SigA

essential: yes

synonyms: sigA, rpoD, crsA

List of homologs in different organisms, belongs to COG0568 (Galperin et al., 2021)

Gene

Coordinates: 2,600,214  2,601,329

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Protein family

• [wiki|Sigma-70 factor family] (according to UniProt)

Structure

• [PDB|3IYD] ([wiki|RNA polymerase] from ''E. coli'', 69% identity) [Pubmed|19903881]
• [AF|P06224]

Modification

• phosphorylated on Arg-365 [Pubmed|31221751]

[wiki|Localization]

• cytoplasm [Pubmed|25313396]

labs

• [wiki|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]

References

Reviews

• 22210308,24308327

Original Publications

• 36815589,12486038,10556308,8107087,14762002,7918363,8071196,7630711,9185571,9287022,14679239,14976210,19735077,2997585,9658000,3127379,10438769,11535782,7599136,9144176,19680289,20525796,22333917,20935043,20817769,23875654,25112476,26582911,19903881,27977677,28539362,28648455,29363854,31221751,32127479,34530448,34898263,35241653,37350110,37728605,38348908