Difference between revisions of "SboA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | ||
| + | {{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[AbrB regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[ResD regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[Rok regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 00:24, 9 December 2010
- Description: subtilosin A
| Gene name | sboA |
| Synonyms | sbo |
| Essential | no |
| Product | subtilosin A |
| Function | antimicrobial peptide |
| MW, pI | 4 kDa, 4.569 |
| Gene length, protein length | 129 bp, 43 aa |
| Immediate neighbours | ywiB, sboX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
AbrB regulon, ResD regulon, Rok regulon
The gene
Basic information
- Locus tag: BSU37350
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: bacteriocin class V family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: secreted (according to Swiss-Prot)
Database entries
- Structure: 1PXQ
- UniProt: O07623
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mark A Strauch, Benjamin G Bobay, John Cavanagh, Fude Yao, Angelo Wilson, Yoann Le Breton
Abh and AbrB control of Bacillus subtilis antimicrobial gene expression.
J Bacteriol: 2007, 189(21);7720-32
[PubMed:17720793]
[WorldCat.org]
[DOI]
(P p)
Mark Albano, Wiep Klaas Smits, Linh T Y Ho, Barbara Kraigher, Ines Mandic-Mulec, Oscar P Kuipers, David Dubnau
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
J Bacteriol: 2005, 187(6);2010-9
[PubMed:15743949]
[WorldCat.org]
[DOI]
(P p)
M M Nakano, G Zheng, P Zuber
Dual control of sbo-alb operon expression by the Spo0 and ResDE systems of signal transduction under anaerobic conditions in Bacillus subtilis.
J Bacteriol: 2000, 182(11);3274-7
[PubMed:10809710]
[WorldCat.org]
[DOI]
(P p)
G Zheng, R Hehn, P Zuber
Mutational analysis of the sbo-alb locus of Bacillus subtilis: identification of genes required for subtilosin production and immunity.
J Bacteriol: 2000, 182(11);3266-73
[PubMed:10809709]
[WorldCat.org]
[DOI]
(P p)
G Zheng, L Z Yan, J C Vederas, P Zuber
Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin.
J Bacteriol: 1999, 181(23);7346-55
[PubMed:10572140]
[WorldCat.org]
[DOI]
(P p)
