SapB

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  • Description: a specific mutant activates alkaline phosphatase during sporulation independently of SigF and SigE

Gene name sapB
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: sapB
MW, pI 25 kDa, 9.484
Gene length, protein length 696 bp, 232 aa
Immediate neighbours yerI, opuE
Sequences Protein DNA Advanced_DNA
Genetic context
SapB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SapB expression.png
























Categories containing this gene/protein

phosphate metabolism, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU06650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: mgtC/sapB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Michael B Whalen, Patrick J Piggot
Gain-of-function mutation of sapB that affects formation of alkaline phosphatase by Bacillus subtilis in sporulation conditions.
Microbiology (Reading): 1997, 143 ( Pt 2);577-583
[PubMed:9043134] [WorldCat.org] [DOI] (P p)