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  • Description: RNase Mini-III

Gene name mrnC
Synonyms yazC
Essential no
Product RNase Mini-III
Function maturation of 23S rRNA
MW, pI 16 kDa, 9.153
Gene length, protein length 429 bp, 143 aa
Immediate neighbours cysS, yacO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YazC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU00950

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RNase III family (but lacks the dsRNA-binding domain)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: T-box, overlaps a transcription terminator upstream of cysE: transcription antitermination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

David Bechhofer, Mount Sinai School, New York, USA Homepage

Your additional remarks

References

Yulia Redko, Ciarán Condon
Ribosomal protein L3 bound to 23S precursor rRNA stimulates its maturation by Mini-III ribonuclease.
Mol Microbiol: 2009, 71(5);1145-54
[PubMed:19154332] [WorldCat.org] [DOI] (I p)

  1. Redko, Y. & Condon, C. (2009) Ribosomal protein L3 bound to 23S precursor rRNA stimulates its maturation by Mini-III ribonuclease. Mol. Microbiol. 71: 1145-1154. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed