Difference between revisions of "Sandbox"

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* '''Description:''' methionyl-tRNA formyltransferase <br/><br/>
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* '''Description:''' Hallo Jörg, das Programm zur Reparatur der KEGG-Links steht. Da jedoch meine KEGG-Genliste schon einige Tage alt ist, gleiche ich sie zuvor mit der jetzt bestehenden SubtiWiki-Hauptseitenversion ab. Danach findet dann die Reparatur statt. <br/><br/>
  
 
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Revision as of 17:39, 24 June 2009

  • Description: Hallo Jörg, das Programm zur Reparatur der KEGG-Links steht. Da jedoch meine KEGG-Genliste schon einige Tage alt ist, gleiche ich sie zuvor mit der jetzt bestehenden SubtiWiki-Hauptseitenversion ab. Danach findet dann die Reparatur statt.

Gene name fmt
Synonyms yloL
Essential yes PubMed
Product methionyl-tRNA formyltransferase
Function formylation of Met-tRNA(fMet)
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging
MW, pI 34 kDa, 5.618
Gene length, protein length 951 bp, 317 aa
Immediate neighbours def, yloM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Fmt context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU15730

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H2O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet) (according to Swiss-Prot)
  • Protein family: fmt family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Yann Duroc, Carmela Giglione, Thierry Meinnel
Mutations in three distinct loci cause resistance to peptide deformylase inhibitors in Bacillus subtilis.
Antimicrob Agents Chemother: 2009, 53(4);1673-8
[PubMed:19171795] [WorldCat.org] [DOI] (I p)

Krzysztof Hinc, Adam Iwanicki, Simone Seror, Michał Obuchowski
Mapping of a transcription promoter located inside the priA gene of the Bacillus subtilis chromosome.
Acta Biochim Pol: 2006, 53(3);497-505
[PubMed:16964327] [WorldCat.org] (P p)