RsbP

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  • Description: protein serine phosphatase, energy PP2C, dephosphorylates RsbV

Gene name rsbP
Synonyms yvfP
Essential no
Product protein serine phosphatase, energy PP2C
Function control of SigB activity
MW, pI 45 kDa, 4.827
Gene length, protein length 1209 bp, 403 aa
Immediate neighbours rsbQ, yvfO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RsbP context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Masatomo Makino, Shinpei Kondo, Tomonori Kaneko, Seiki Baba, Kunio Hirata, Takashi Kumasaka
Expression, crystallization and preliminary crystallographic analysis of the PAS domain of RsbP, a stress-response phosphatase from Bacillus subtilis.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2009, 65(Pt 6);559-61
[PubMed:19478430] [WorldCat.org] [DOI] (I p)

Margaret S Brody, Valley Stewart, Chester W Price
Bypass suppression analysis maps the signalling pathway within a multidomain protein: the RsbP energy stress phosphatase 2C from Bacillus subtilis.
Mol Microbiol: 2009, 72(5);1221-34
[PubMed:19432806] [WorldCat.org] [DOI] (I p)

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed