RsbP

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Gene name rsbP
Synonyms yvfP
Essential no
Product protein serine phosphatase, energy PP2C
Function control of SigB activity
Gene expression levels in SubtiExpress: rsbP
Interactions involving this protein in SubtInteract: RsbP
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 45 kDa, 4.827
Gene length, protein length 1209 bp, 403 aa
Immediate neighbours rsbQ, ganB
Sequences Protein DNA DNA_with_flanks
Genetic context
RsbP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RsbP expression.png




























Categories containing this gene/protein

protein modification, sigma factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU34110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: dephosphorylation of RsbV in response to red light, this results in SigB activation PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • activity is stimulated upon interaction of the RsbP oligomer with RsbQ PubMed

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed

Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB  
Stochastic pulse regulation in bacterial stress response. 
Science. 2011 334:366-369. 
PubMed:21979936