RsbP

From SubtiWiki
Revision as of 09:29, 23 April 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
Gene name rsbP
Synonyms yvfP
Essential no
Product protein serine phosphatase, energy PP2C
Function control of SigB activity
Interactions involving this protein in SubtInteract: RsbP
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 45 kDa, 4.827
Gene length, protein length 1209 bp, 403 aa
Immediate neighbours rsbQ, yvfO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RsbP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RsbP expression.png




























Categories containing this gene/protein

protein modification, sigma factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU34110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: dephosphorylation of RsbV in response to red light, this results in SigB activation PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • activity is stimulated upon interaction of the RsbP oligomer with RsbQ PubMed

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed

Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB  
Stochastic pulse regulation in bacterial stress response. 
Science. 2011 334:366-369. 
PubMed:21979936