Difference between revisions of "RpsO"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[translation]]}},
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{{SubtiWiki category|[[essential genes]]}}
 
=The protein=
 
=The protein=
  

Revision as of 19:35, 30 November 2010

Gene name rpsO
Synonyms
Essential yes PubMed
Product ribosomal protein S15 (BS18)
Function translation
MW, pI 10 kDa, 10.975
Gene length, protein length 267 bp, 89 aa
Immediate neighbours ribC, pnpA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RpsO context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16680

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

translation, essential genes

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 1A32 (Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is processed, this is initiated by RNase Y and cleavage products are subsequently subject to exonucleolytic degradation by RNases J1 and J2 and by PNPase PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Shiyi Yao, David H Bechhofer
Initiation of decay of Bacillus subtilis rpsO mRNA by endoribonuclease RNase Y.
J Bacteriol: 2010, 192(13);3279-86
[PubMed:20418391] [WorldCat.org] [DOI] (I p)

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Shiyi Yao, David H Bechhofer
Processing and stability of inducibly expressed rpsO mRNA derivatives in Bacillus subtilis.
J Bacteriol: 2009, 191(18);5680-9
[PubMed:19633085] [WorldCat.org] [DOI] (I p)

G M Culver, J H Cate, G Z Yusupova, M M Yusupov, H F Noller
Identification of an RNA-protein bridge spanning the ribosomal subunit interface.
Science: 1999, 285(5436);2133-6
[PubMed:10497132] [WorldCat.org] [DOI] (P p)