RplB
- Description: ribosomal protein L2, required for assembly of RplP into the 50S subunit of the ribosome
| Gene name | rplB |
| Synonyms | |
| Essential | yes PubMed |
| Product | ribosomal protein L2 (BL2) |
| Function | translation |
| Gene expression levels in SubtiExpress: rplB | |
| Interactions involving this protein in SubtInteract: RplB | |
| MW, pI | 30 kDa, 11.013 |
| Gene length, protein length | 831 bp, 277 aa |
| Immediate neighbours | rplW, rpsS |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
translation, essential genes, universally conserved proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01190
Phenotypes of a mutant
- essential PubMed
- a H142L mutation results in a temperature-sensitive phenotype and is acompanied by growth and sporulation defects, the mutation can be suppressed by increased expression of yaaA PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ribosomal protein L2P family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure: 1RL2 (L2 RNA-binding domain, Geobacillus stearothermophilus)
- UniProt: P42919
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon: rpsJ-rplC-rplD-rplW-rplB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ-rplN-rplX-rplE-rpsN-rpsH-rplF-rplR-rpsE-rpmD-rplO PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
