Rpe

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  • Description: ribulose 5-phosphate 3-epimerase

Gene name rpe
Synonyms yloR
Essential no
Product ribulose 5-phosphate 3-epimerase
Function pentose phosphate pathway
Gene expression levels in SubtiExpress: rpe
Metabolic function and regulation of this protein in SubtiPathways:
rpe
MW, pI 23 kDa, 5.651
Gene length, protein length 651 bp, 217 aa
Immediate neighbours cpgA, yloS
Sequences Protein DNA DNA_with_flanks
Genetic context
Rpe context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Rpe expression.png




























Categories containing this gene/protein

carbon core metabolism

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15790

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-ribulose 5-phosphate = D-xylulose 5-phosphate (according to Swiss-Prot)
  • Protein family: ribulose-phosphate 3-epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1TQJ (from Synechocystis sp., 61% identity, 75% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:
  • FLAG-tag construct: GP1405 (spc, based on pGP1331), available in the Stülke lab

Labs working on this gene/protein

Your additional remarks

References

Eric L Wise, Julie Akana, John A Gerlt, Ivan Rayment
Structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 A resolution.
Acta Crystallogr D Biol Crystallogr: 2004, 60(Pt 9);1687-90
[PubMed:15333955] [WorldCat.org] [DOI] (P p)