Difference between revisions of "Rpe"

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Revision as of 09:21, 19 April 2012

  • Description: ribulose 5-phosphate 3-epimerase

Gene name rpe
Synonyms yloR
Essential no
Product ribulose 5-phosphate 3-epimerase
Function pentose phosphate pathway
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 23 kDa, 5.651
Gene length, protein length 651 bp, 217 aa
Immediate neighbours cpgA, yloS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Rpe context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Rpe expression.png




























Categories containing this gene/protein

carbon core metabolism

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15790

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-ribulose 5-phosphate = D-xylulose 5-phosphate (according to Swiss-Prot)
  • Protein family: ribulose-phosphate 3-epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1TQJ (from Synechocystis sp., 61% identity, 75% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:
  • FLAG-tag construct: GP1405 (spc, based on pGP1331), available in the Stülke lab

Labs working on this gene/protein

Your additional remarks

References

Eric L Wise, Julie Akana, John A Gerlt, Ivan Rayment
Structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 A resolution.
Acta Crystallogr D Biol Crystallogr: 2004, 60(Pt 9);1687-90
[PubMed:15333955] [WorldCat.org] [DOI] (P p)