Rok

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  • Description: repressor of comK

Gene name rok
Synonyms ykuW
Essential no
Product transcriptional repressor
Function regulation of genetic competence
MW, pI 21 kDa, 9.701
Gene length, protein length 573 bp, 191 aa
Immediate neighbours ykuV, yknT
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Rok context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Locus tag: BSU14240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

Tran Thu Hoa, Pablo Tortosa, Mark Albano, David Dubnau
Rok (YkuW) regulates genetic competence in Bacillus subtilis by directly repressing comK.
Mol Microbiol: 2002, 43(1);15-26
[PubMed:11849533] [WorldCat.org] [DOI] (P p)

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed