Rny

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  • Description: Rny catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP and is a putative RNase

Gene name rny
Synonyms ymdA
Essential yes
Product 2',3'-cyclic-nucleotide 2'-phosphodiesterase
Function hydrolysis of AMP and GMP& putative RNase
MW, pI 58,7 kDa, 5.39
Gene length, protein length 1560 bp, 520 amino acids
Immediate neighbours pdbX, ymdB
Gene sequence (+200bp) Protein sequence
Genetic context
File:GenE context.gif












The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry:
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 3'-phosphate
  • Protein family: 2',3' cyclic nucleotide phosphodiesterase family
  • Paralogous protein(s): similar to unknown proteins

Extended information on the protein

  • Kinetic information:
  • Domains:
    • transmembrane domain (4–24)
    • KH domain (210–273)
    • HD domain (336–429)
  • Modification:
  • Cofactor(s): metal-dependent
  • Effectors of protein activity:
  • Interactions:
  • Localization: Single-pass membrane protein

Database entries

  • Structure:
  • Swiss prot entry: [2]
  • KEGG entry: [3]
  • E.C. number: [4]

Additional information

required for processing of gapA operon mRNA

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed