Difference between revisions of "Rny"

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(References)
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* '''Description:''' Rny catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP and is a putative RNase <br/><br/>
+
* '''Description:''' required for the processing of the ''[[gapA]]'' operon mRNA<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || 2',3'-cyclic-nucleotide 2'-phosphodiesterase
+
|style="background:#ABCDEF;" align="center"| '''Product''' ||  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || hydrolysis of AMP and GMP& putative RNase
+
|style="background:#ABCDEF;" align="center"|'''Function''' || required for the processing of the ''[[gapA]]'' operon mRNA
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58,7 kDa, 5.39
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58,7 kDa, 5.39
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 3'-phosphate
+
* '''Catalyzed reaction/ biological activity:''' required for the processing of the ''[[gapA]]'' operon mRNA
  
 
* '''Protein family:''' 2',3' cyclic nucleotide phosphodiesterase family
 
* '''Protein family:''' 2',3' cyclic nucleotide phosphodiesterase family
  
* '''Paralogous protein(s):''' similar to unknown proteins
+
* '''Paralogous protein(s):'''  
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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=== Additional information===
 
=== Additional information===
required for processing of gapA operon mRNA
 
  
 +
required for the processing of the ''[[gapA]]'' operon mRNA
 
=Expression and regulation=
 
=Expression and regulation=
  

Revision as of 10:12, 9 January 2009

  • Description: required for the processing of the gapA operon mRNA

Gene name rny
Synonyms ymdA
Essential yes
Product
Function required for the processing of the gapA operon mRNA
MW, pI 58,7 kDa, 5.39
Gene length, protein length 1560 bp, 520 amino acids
Immediate neighbours pdbX, ymdB
Gene sequence (+200bp) Protein sequence
Genetic context
File:GenE context.gif












The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry:
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: required for the processing of the gapA operon mRNA
  • Protein family: 2',3' cyclic nucleotide phosphodiesterase family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • transmembrane domain (4–24)
    • KH domain (210–273)
    • HD domain (336–429)
  • Modification:
  • Cofactor(s): metal-dependent
  • Effectors of protein activity:
  • Interactions:
  • Localization: Single-pass membrane protein

Database entries

  • Structure:
  • Swiss prot entry: [2]
  • KEGG entry: [3]
  • E.C. number: [4]

Additional information

required for the processing of the gapA operon mRNA

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

Labs working on this gene/protein

Jörg Stülke, University of Göttingen, Germany Homepage

Your additional remarks

References

  1. Commichau, F. M., Rothe, F. M., Herzberg, C., Wagner, E., Hellwig, D., Lehnik-Habrink, M., Hammer, E., Völker, U. & Stülke, J. Novel activities of glycolytic enzymes in Bacillus subtilis: Interactions with essential proteins involved in mRNA processing. subm.
  2. Hunt, A., Rawlins, J. P., Thomaides, H. B., and Errington, J. (2006) Functional analysis of 11 putative essential genes in Bacillus subtilis. Microbiology 152, 2895-2907. PubMed