Rex

From SubtiWiki
Revision as of 09:36, 14 May 2013 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: transcriptional repressor of anaerobically expressed genes involved in anaerobic respiration and fermentation

Gene name rex
Synonyms ydiH
Essential no
Product transcriptional repressor
Function regulation of fermentation and anaerobic respiration
Gene expression levels in SubtiExpress: rex
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 23 kDa, 6.772
Gene length, protein length 645 bp, 215 aa
Immediate neighbours ydiG, tatAY
Sequences Protein DNA DNA_with_flanks
Genetic context
YdiH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Rex expression.png



















Categories containing this gene/protein

regulators of electron transport, carbon core metabolism, transcription factors and their control

This gene is a member of the following regulons

The Rex regulon

The gene

Basic information

  • Locus tag: BSU05970

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transcriptional regulatory rex family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: NADH (indication of low oxygen concentration) releases Rex from DNA PubMed, Rex has a very highh affinity for NADH

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant: LUW292 (erm), GP834 (erm), both available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Claes von Wachenfeldt, Lund University, Sweden Homepage

Your additional remarks

References

Reviews

Elisabeth Härtig, Dieter Jahn
Regulation of the anaerobic metabolism in Bacillus subtilis.
Adv Microb Physiol: 2012, 61;195-216
[PubMed:23046954] [WorldCat.org] [DOI] (I p)

Original publications