Difference between revisions of "Response regulator aspartate phosphatases"

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* [[RapD]]: [[RapD]] inhibits the DNA-binding activity of [[ComA]]-P
 
* [[RapD]]: [[RapD]] inhibits the DNA-binding activity of [[ComA]]-P
 
* [[RapE]], [[PhrE]]: [[RapE]] dephosphorylates [[Spo0F]]-P
 
* [[RapE]], [[PhrE]]: [[RapE]] dephosphorylates [[Spo0F]]-P
 +
* [[RapF]], [[PhrF]]: [[RapF]] inhibits the DNA-binding activity of [[ComA]]-P
 +
* [[RapG]], [[PhrG]]: [[RapG]] inhibits the DNA-binding activity of [[DegU]]-P
 +
* [[RapH]]: bifuntional protein: dephosphorylates [[Spo0F]]-P and inhibits the DNA-binding activity of [[ComA]]-P
 +
* [[RapI]], [[PhrI]]: [[RapI]] inhibits the DNA-binding activity of [[ImmR]]
 +
* [[RapJ]]: unknown function
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* [[RapK]], [[PhrK]]: [[RapK]] inhibits the DNA-binding activity of [[ComA]]-P
  
 
==Related lists==
 
==Related lists==
 
* [[two-component systems]]
 
* [[two-component systems]]
 
* [[phosphorelay]]
 
* [[phosphorelay]]
 +
 +
==Reviews==
 +
<pubmed>8730857 11587783 </pubmed>

Revision as of 20:38, 29 November 2009

These proteins contain the so-called tetratricopeptide repeats (TPRs) protein-protein interaction module. They control the phosphorelay for sporulation initiation by dephosphorylating Spo0F-P or they inhibit transcription factors by protein-protein interaction (without affecting phosphorylation). The activity of these proteins can be controlled by small peptides that are expressed as precursors, exported, and re-imported into the cell.

The RAP proteins of B. subtilis, their cognate peptides and target proteins

Related lists

Reviews

M Perego, J A Brannigan
Pentapeptide regulation of aspartyl-phosphate phosphatases.
Peptides: 2001, 22(10);1541-7
[PubMed:11587783] [WorldCat.org] [DOI] (P p)

M Perego, P Glaser, J A Hoch
Aspartyl-phosphate phosphatases deactivate the response regulator components of the sporulation signal transduction system in Bacillus subtilis.
Mol Microbiol: 1996, 19(6);1151-7
[PubMed:8730857] [WorldCat.org] [DOI] (P p)