resC

168

part of heam translocase, required for cytochrome c synthesis

locus: BSU_23130

Molecular weight: 39.61 kDa

pI: 9.56

Protein length: 391 aa

Gene length: 1176 bp

function: cytochrome c biogenesis

product: part of the [protein|495721E4B8BF6FEC01E62E86339560F90776EED1|resB]-[protein|97FE84CF968596AC39D19EE2E43DA625147FD702|resC] haem translocase

essential: no

synonyms: resC, ypxC

List of homologs in different organisms, belongs to COG0755 (Galperin et al., 2021)

Gene

Coordinates: 2,417,984  2,419,159

Phenotypes of a mutant

• essential [Pubmed|12682299], non-essential according to [Pubmed|28189581]

Advertisement

The protein

Catalyzed reaction/ biological activity

• haem-binding protein,  translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane [Pubmed|19682263]

Protein family

• CcmF/CycK/Ccl1/NrfE/CcsA family (single member, according to UniProt)

Structure

• [AF|P35162]

[wiki|Localization]

• cytoplasma membrane [Pubmed|19682263]

Biological materials

Mutant

• BKE23130 ([gene|97FE84CF968596AC39D19EE2E43DA625147FD702|resC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23130 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGCCATGACATCACTCCCTT,  downstream forward: _UP4_TAGTCCTTTGAAAGCGACAC
• BKK23130 ([gene|97FE84CF968596AC39D19EE2E43DA625147FD702|resC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23130 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGCCATGACATCACTCCCTT,  downstream forward: _UP4_TAGTCCTTTGAAAGCGACAC

References

Reviews

• 35630371

Original Publications

• 10844653,19682263,8631715,11222591,9988472,17706591,16825793,28189581