Difference between revisions of "RecU"

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Revision as of 13:43, 16 May 2013

  • Description: DNA repair, homologous recombination and chromosome segregation; recognizes, distorts, and cleaves four-stranded recombination intermediates and modulates RecA activities

Gene name recU
Synonyms recG, prfA, yppB, jopB
Essential no
Product Holliday junction resolvase
Function DNA repair, homologous recombination and chromosome segregation
Gene expression levels in SubtiExpress: recU
Interactions involving this protein in SubtInteract: RecU
MW, pI 23 kDa, 9.511
Gene length, protein length 618 bp, 206 aa
Immediate neighbours yppC, ponA
Sequences Protein DNA DNA_with_flanks
Genetic context
RecU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RecU expression.png

























Categories containing this gene/protein

DNA repair/ recombination, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU22310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
    • GP891 (recU::cat), available in Stülke lab
    • 1A895 (no resistance), PubMed, available at BGSC
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

RecU in other organisms

Ana R Pereira, Patricia Reed, Helena Veiga, Mariana G Pinho
The Holliday junction resolvase RecU is required for chromosome segregation and DNA damage repair in Staphylococcus aureus.
BMC Microbiol: 2013, 13;18
[PubMed:23356868] [WorldCat.org] [DOI] (I e)