RecN
- Description: DNA repair and genetic recombination
| Gene name | recN |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | DNA repair and genetic recombination |
| Gene expression levels in SubtiExpress: recN | |
| MW, pI | 64 kDa, 4.802 |
| Gene length, protein length | 1728 bp, 576 aa |
| Immediate neighbours | spoIVB, ahrC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: recN family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P17894
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
Reviews
Additional reviews: PubMed
Silvia Ayora, Begoña Carrasco, Paula P Cárdenas, Carolina E César, Cristina Cañas, Tribhuwan Yadav, Chiara Marchisone, Juan C Alonso
Double-strand break repair in bacteria: a view from Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(6);1055-81
[PubMed:21517913]
[WorldCat.org]
[DOI]
(I p)
Peter L Graumann, Tobias Knust
Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair.
Chromosome Res: 2009, 17(2);265-75
[PubMed:19308706]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
Dawit Kidane, Begoña Carrasco, Candela Manfredi, Katharina Rothmaier, Silvia Ayora, Serkalem Tadesse, Juan C Alonso, Peter L Graumann
Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells.
PLoS Genet: 2009, 5(9);e1000630
[PubMed:19730681]
[WorldCat.org]
[DOI]
(I p)
Lyle A Simmons, Alexi I Goranov, Hajime Kobayashi, Bryan W Davies, Daniel S Yuan, Alan D Grossman, Graham C Walker
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction.
J Bacteriol: 2009, 191(4);1152-61
[PubMed:19060143]
[WorldCat.org]
[DOI]
(I p)
Humberto Sanchez, Paula P Cardenas, Shige H Yoshimura, Kunio Takeyasu, Juan C Alonso
Dynamic structures of Bacillus subtilis RecN-DNA complexes.
Nucleic Acids Res: 2008, 36(1);110-20
[PubMed:17999999]
[WorldCat.org]
[DOI]
(I p)
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
Humberto Sanchez, Dawit Kidane, M Castillo Cozar, Peter L Graumann, Juan C Alonso
Recruitment of Bacillus subtilis RecN to DNA double-strand breaks in the absence of DNA end processing.
J Bacteriol: 2006, 188(2);353-60
[PubMed:16385024]
[WorldCat.org]
[DOI]
(P p)
Humberto Sanchez, Juan C Alonso
Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP.
Nucleic Acids Res: 2005, 33(7);2343-50
[PubMed:15849320]
[WorldCat.org]
[DOI]
(I e)
B E Van Hoy, J A Hoch
Characterization of the spoIVB and recN loci of Bacillus subtilis.
J Bacteriol: 1990, 172(3);1306-11
[PubMed:2106508]
[WorldCat.org]
[DOI]
(P p)
