RbsD

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  • Description: ribose ABC transporter (membrane protein)

Gene name rbsD
Synonyms
Essential no
Product ribose ABC transporter (membrane protein)
Function ribose uptake
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 14 kDa, 4.987
Gene length, protein length 393 bp, 131 aa
Immediate neighbours rbsK, rbsA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RbsD context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU35930

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Beta-D-ribopyranose = beta-D-ribofuranose (according to Swiss-Prot)
  • Protein family: RbsD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 1OGD (complex with D-ribose)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed upon transition into the stationary phase (AbrB) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Le Thi Tam, Christine Eymann, Dirk Albrecht, Rabea Sietmann, Frieder Schauer, Michael Hecker, Haike Antelmann
Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis.
Environ Microbiol: 2006, 8(8);1408-27
[PubMed:16872404] [WorldCat.org] [DOI] (P p)

Min-Sung Kim, Joon Shin, Weontae Lee, Heung-Soo Lee, Byung-Ha Oh
Crystal structures of RbsD leading to the identification of cytoplasmic sugar-binding proteins with a novel folding architecture.
J Biol Chem: 2003, 278(30);28173-80
[PubMed:12738765] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

M A Strauch
AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon.
J Bacteriol: 1995, 177(23);6727-31
[PubMed:7592460] [WorldCat.org] [DOI] (P p)

K Woodson, K M Devine
Analysis of a ribose transport operon from Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 8);1829-38
[PubMed:7921236] [WorldCat.org] [DOI] (P p)