Difference between revisions of "RbgA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly
 
|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU16050 rbgA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16050 rbgA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 9.528   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 9.528   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rplS]]'', ''[[rnhB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rplS]]'', ''[[rnhB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13478&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16050 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ylqF_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylqF_context.gif]]

Revision as of 13:49, 13 May 2013

  • Description: assembly of the 50S subunit of the ribosome

Gene name rbgA
Synonyms ylqF
Essential yes PubMed
Product GTPase
Function ribosome assembly
Gene expression levels in SubtiExpress: rbgA
MW, pI 31 kDa, 9.528
Gene length, protein length 846 bp, 282 aa
Immediate neighbours rplS, rnhB
Sequences Protein DNA Advanced_DNA
Genetic context
YlqF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RbgA expression.png















Categories containing this gene/protein

translation, essential genes, GTP-binding proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU16050

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
  • Protein family: MTG1 subfamily (according to Swiss-Prot) Era/Obg family

Extended information on the protein

  • Kinetic information:
  • Domains:
    • RNA-binding domain at the C-terminus PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Naotake Ogasawara, Nara, Japan

Your additional remarks

References

Reviews

Natalie Verstraeten, Maarten Fauvart, Wim Versées, Jan Michiels
The universally conserved prokaryotic GTPases.
Microbiol Mol Biol Rev: 2011, 75(3);507-42, second and third pages of table of contents
[PubMed:21885683] [WorldCat.org] [DOI] (I p)

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)


Original publications

Additional publications: PubMed