Difference between revisions of "RatA"

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(References)
(Expression and regulation)
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''  
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* '''Additional information:'''
 +
** the ''[[txpA]]'' mRNA-''[[RatA]]'' RNA duplex is degraded by [[rnc|RNase III]] {{PubMed|23300471}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 14:58, 10 January 2013

  • Description: regulatory RNA, ncRNA, antisense for txpA

Gene name ratA
Synonyms
Essential no
Product txpA antisense RNA
Function control of txpA expression
Gene length 222 bp
Immediate neighbours txpA, bsrH
Gene sequence (+200bp)
Genetic context
File:GenE context.gif



Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element, ncRNA

This gene is a member of the following regulons

The ratA regulon: txpA

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry:
  • Structure:

Additional information

The RNA

binds the txpA mRNA and triggers its degradation PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard University, Cambridge, USA Homepage

Your additional remarks

References

Reviews

Fabian M Commichau, Jörg Stülke
A mystery unraveled: essentiality of RNase III in Bacillus subtilis is caused by resident prophages.
PLoS Genet: 2012, 8(12);e1003199
[PubMed:23300472] [WorldCat.org] [DOI] (I p)


Original publications

Additional publications: PubMed

Jessica M Silvaggi, John B Perkins, Richard Losick
Small untranslated RNA antitoxin in Bacillus subtilis.
J Bacteriol: 2005, 187(19);6641-50
[PubMed:16166525] [WorldCat.org] [DOI] (P p)