Difference between revisions of "RapJ"
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| − | * '''Description:''' [[response regulator aspartate phosphatase]]<br/><br/> | + | * '''Description:''' [[response regulator aspartate phosphatase]], dephosphorylates [[Spo0F]]-P<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[response regulator aspartate phosphatase]] | |style="background:#ABCDEF;" align="center"| '''Product''' || [[response regulator aspartate phosphatase]] | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of the [[phosphorelay]] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02820 rapJ] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02820 rapJ] | ||
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RapJ RapJ] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 4.902 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 4.902 | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[protein modification]]}}, | {{SubtiWiki category|[[protein modification]]}}, | ||
| + | {{SubtiWiki category|[[phosphorelay]]}}, | ||
{{SubtiWiki category|[[transcription factors and their control]]}} | {{SubtiWiki category|[[transcription factors and their control]]}} | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** dephosphorylates [[Spo0F]]-P {{PubMed|21346797}} | ||
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| + | ** the interaction with [[PhrC]] inactivates [[RapJ]] {{PubMed|23526881}} | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[RapJ]]-[[Spo0F]], dephosphorylation of [[Spo0F]]-P {{PubMed|21346797}} | ||
| + | ** [[RapJ]]-[[PhrC]] {{PubMed|23526881}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
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=Your additional remarks= | =Your additional remarks= | ||
=References= | =References= | ||
| − | + | <pubmed>21346797 23526881 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:20, 27 March 2013
- Description: response regulator aspartate phosphatase, dephosphorylates Spo0F-P
| Gene name | rapJ |
| Synonyms | ycdE |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of the phosphorelay |
| Gene expression levels in SubtiExpress: rapJ | |
| Interactions involving this protein in SubtInteract: RapJ | |
| MW, pI | 44 kDa, 4.902 |
| Gene length, protein length | 1119 bp, 373 aa |
| Immediate neighbours | cwlK, ycdF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
protein modification, phosphorelay, transcription factors and their control
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02820
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
Database entries
- Structure:
- UniProt: O34327
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rapJ (according to DBTBS)
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Vijay Parashar, Philip D Jeffrey, Matthew B Neiditch
Conformational change-induced repeat domain expansion regulates Rap phosphatase quorum-sensing signal receptors.
PLoS Biol: 2013, 11(3);e1001512
[PubMed:23526881]
[WorldCat.org]
[DOI]
(I p)
Vijay Parashar, Nicolas Mirouze, David A Dubnau, Matthew B Neiditch
Structural basis of response regulator dephosphorylation by Rap phosphatases.
PLoS Biol: 2011, 9(2);e1000589
[PubMed:21346797]
[WorldCat.org]
[DOI]
(I e)
