Difference between revisions of "RadC"

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The ''radC'' locus is the chromosomal integration site for the φ105 prophage [http://www.ncbi.nlm.nih.gov/pubmed/24009114 Pubmed]
  
 
=References=
 
=References=

Revision as of 01:39, 8 June 2014

  • Description: probable DNA repair protein

Gene name radC
Synonyms ysxA
Essential no
Product probable DNA repair protein
Function DNA repair
Gene expression levels in SubtiExpress: radC
MW, pI 25 kDa, 7.829
Gene length, protein length 693 bp, 231 aa
Immediate neighbours mreB, maf
Sequences Protein DNA DNA_with_flanks
Genetic context
RadC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RadC expression.png
























Categories containing this gene/protein

DNA repair/ recombination, genetic competence, cell envelope stress proteins (controlled by SigM, V, W, X, Y), phosphoproteins

This gene is a member of the following regulons

ComK regulon, SigM regulon

The gene

Basic information

  • Locus tag: BSU28040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: radC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-59 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress (SigM) PubMed
    • expression is reduced in a SigV mutant PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

The radC locus is the chromosomal integration site for the φ105 prophage Pubmed

References

Additional publications: PubMed