Difference between revisions of "RadC"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''radC'' (according to [http://dbtbs.hgc.jp/COG/prom/radC.html DBTBS])
  
* '''[[Sigma factor]]:''' [[SigM]]
+
* '''[[Sigma factor]]:''' [[SigM]] {{PubMed|12775685}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress ([[SigM]]) {{PubMed|12775685}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
  
<pubmed>17434969,,16479537 </pubmed>
+
<pubmed>17434969,,16479537 12775685 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:32, 13 December 2009

  • Description: probable DNA repair protein

Gene name radC
Synonyms ysxA
Essential no
Product probable DNA repair protein
Function DNA repair
MW, pI 25 kDa, 7.829
Gene length, protein length 693 bp, 231 aa
Immediate neighbours mreB, maf
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RadC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: radC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: Cytoplasm (Homogeneous) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: radC (according to DBTBS)
  • Regulation:
    • expressed in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress (SigM) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Adrian J Jervis, Penny D Thackray, Chris W Houston, Malcolm J Horsburgh, Anne Moir
SigM-responsive genes of Bacillus subtilis and their promoters.
J Bacteriol: 2007, 189(12);4534-8
[PubMed:17434969] [WorldCat.org] [DOI] (P p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Penny D Thackray, Anne Moir
SigM, an extracytoplasmic function sigma factor of Bacillus subtilis, is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress.
J Bacteriol: 2003, 185(12);3491-8
[PubMed:12775685] [WorldCat.org] [DOI] (P p)