RNases

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RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs

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RNA degradosome




Labs working on RNases

Exoribonucleases

  • RNase J1: 5'-3' activity, does also have endonuclease activity

Endoribonucleases

  • RNase J1: ssRNA endonuclease, does also have exonuclease activity
  • RNase J2: ssRNA endonuclease, may also have exonuclease activity

Reviews on RNases in Bacillus subtilis

Ciarán Condon, David H Bechhofer
Regulated RNA stability in the Gram positives.
Curr Opin Microbiol: 2011, 14(2);148-54
[PubMed:21334965] [WorldCat.org] [DOI] (I p)

Cecília M Arraiano, José M Andrade, Susana Domingues, Inês B Guinote, Michal Malecki, Rute G Matos, Ricardo N Moreira, Vânia Pobre, Filipa P Reis, Margarida Saramago, Inês J Silva, Sandra C Viegas
The critical role of RNA processing and degradation in the control of gene expression.
FEMS Microbiol Rev: 2010, 34(5);883-923
[PubMed:20659169] [WorldCat.org] [DOI] (I p)

Flore Sinturel, Olivier Pellegrini, Song Xiang, Liang Tong, Ciarán Condon, Lionel Bénard
Real-time fluorescence detection of exoribonucleases.
RNA: 2009, 15(11);2057-62
[PubMed:19767421] [WorldCat.org] [DOI] (I p)

David H Bechhofer
Messenger RNA decay and maturation in Bacillus subtilis.
Prog Mol Biol Transl Sci: 2009, 85;231-73
[PubMed:19215774] [WorldCat.org] [DOI] (P p)

Ciarán Condon
RNA processing and degradation in Bacillus subtilis.
Microbiol Mol Biol Rev: 2003, 67(2);157-74, table of contents
[PubMed:12794188] [WorldCat.org] [DOI] (P p)

Ciarán Condon, Harald Putzer
The phylogenetic distribution of bacterial ribonucleases.
Nucleic Acids Res: 2002, 30(24);5339-46
[PubMed:12490701] [WorldCat.org] [DOI] (I p)


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