Difference between revisions of "RNA switch"

From SubtiWiki
Jump to: navigation, search
(List of Bacillus subtilis RNAswitches)
(List of Bacillus subtilis RNAswitches)
Line 21: Line 21:
 
* potential additional RNA switches
 
* potential additional RNA switches
 
The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.
 
The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.
 +
 
** [http://rfam.sanger.ac.uk/family?acc=RF00379 ydaO-yuaA switch]: ''[[ydaO]], [[ktrA]]''
 
** [http://rfam.sanger.ac.uk/family?acc=RF00379 ydaO-yuaA switch]: ''[[ydaO]], [[ktrA]]''
** ykkC-yxkD switch: ''[[ykkC]], [[yxkD]]''
+
** [http://rfam.sanger.ac.uk/family?acc=RF00442 ykkC-yxkD switch]: ''[[ykkC]], [[yxkD]]''
 
** [http://rfam.sanger.ac.uk/family?acc=RF00080 yybP-ykoY switch]: ''[[yybP]]'', ''[[ykoY]]''
 
** [http://rfam.sanger.ac.uk/family?acc=RF00080 yybP-ykoY switch]: ''[[yybP]]'', ''[[ykoY]]''
** ylbH switch: ''[[ylbH]]''
+
** [http://rfam.sanger.ac.uk/family?acc=RF00516 ylbH switch]: ''[[ylbH]]''
** L10_leader
+
** [http://rfam.sanger.ac.uk/family?acc=RF00557 L10 leader]: ''[[rplJ]]''
 
** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]''
 
** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]''
** L19_leader
+
** L19 leader: ''[[rplS]]''
** L20_leader
+
** [http://rfam.sanger.ac.uk/family?acc=RF00558 L20 leader]: in front of the ''[[infC]]-[[rpmL]]-[[rplT]]'' operon
** L21_leader
+
** [http://rfam.sanger.ac.uk/family?acc=RF00559 L21_leader]:in front of the ''[[rplU]]-[[ysxB]]-[[rpmA]]'' operon
  
 
==Important Reviews==
 
==Important Reviews==
  
 
<pubmed>15063848 , 19250859 ,19141470 , 17092822, 17764952 ,17381303, 16226486 , 16153177 , 15750802, 14523920  </pubmed>
 
<pubmed>15063848 , 19250859 ,19141470 , 17092822, 17764952 ,17381303, 16226486 , 16153177 , 15750802, 14523920  </pubmed>

Revision as of 13:54, 7 July 2009

RNA switches are regulatory systems that rely on alternative mRNA structures.

RNA switches may be triggered by proteins, tRNAs (T-box), or metabolites (riboswitches)

List of Bacillus subtilis RNAswitches

  • Protein-dependent RNA switches
  • potential additional RNA switches

The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.

Important Reviews

Michael D Dambach, Wade C Winkler
Expanding roles for metabolite-sensing regulatory RNAs.
Curr Opin Microbiol: 2009, 12(2);161-9
[PubMed:19250859] [WorldCat.org] [DOI] (I p)

Tina M Henkin
Riboswitch RNAs: using RNA to sense cellular metabolism.
Genes Dev: 2008, 22(24);3383-90
[PubMed:19141470] [WorldCat.org] [DOI] (P p)

Catherine A Wakeman, Wade C Winkler, Charles E Dann
Structural features of metabolite-sensing riboswitches.
Trends Biochem Sci: 2007, 32(9);415-24
[PubMed:17764952] [WorldCat.org] [DOI] (P p)

Irnov, A Kertsburg, W C Winkler
Genetic control by cis-acting regulatory RNAs in Bacillus subtilis: general principles and prospects for discovery.
Cold Spring Harb Symp Quant Biol: 2006, 71;239-49
[PubMed:17381303] [WorldCat.org] [DOI] (P p)

Frank J Grundy, Tina M Henkin
From ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangements.
Crit Rev Biochem Mol Biol: 2006, 41(6);329-38
[PubMed:17092822] [WorldCat.org] [DOI] (P p)

Wade C Winkler
Riboswitches and the role of noncoding RNAs in bacterial metabolic control.
Curr Opin Chem Biol: 2005, 9(6);594-602
[PubMed:16226486] [WorldCat.org] [DOI] (P p)

Wade C Winkler, Ronald R Breaker
Regulation of bacterial gene expression by riboswitches.
Annu Rev Microbiol: 2005, 59;487-517
[PubMed:16153177] [WorldCat.org] [DOI] (P p)

Wade C Winkler
Metabolic monitoring by bacterial mRNAs.
Arch Microbiol: 2005, 183(3);151-9
[PubMed:15750802] [WorldCat.org] [DOI] (P p)

Frank J Grundy, Tina M Henkin
Regulation of gene expression by effectors that bind to RNA.
Curr Opin Microbiol: 2004, 7(2);126-31
[PubMed:15063848] [WorldCat.org] [DOI] (P p)

Wade C Winkler, Ronald R Breaker
Genetic control by metabolite-binding riboswitches.
Chembiochem: 2003, 4(10);1024-32
[PubMed:14523920] [WorldCat.org] [DOI] (P p)