Difference between revisions of "RNA switch"
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(→List of Bacillus subtilis RNAswitches) |
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* '''Protein-dependent RNA switches''' | * '''Protein-dependent RNA switches''' | ||
| + | ** [http://rfam.sanger.ac.uk/family?acc=RF00558 L20 leader]: in front of the ''[[infC]]-[[rpmI]]-[[rplT]]-[[ysdA]]'' operon: controlled by [[RplT]] binding | ||
| + | ** ''[[ptsG]]-[[ptsH]]-[[ptsI]]'': controlled by [[GlcT]] | ||
| + | ** ''[[sacX]]-[[sacY]]'', ''[[sacB]]'': controlled by [[SacY]] | ||
| + | ** ''[[sacP]]-[[sacA]]'': controlled by [[SacT]] | ||
| + | ** ''[[bglS]]'', ''[[bglP]]-[[bglH]]'': controlled by [[BglP]] | ||
*'''[[T-box]]''' | *'''[[T-box]]''' | ||
| Line 31: | Line 36: | ||
** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]'' | ** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]'' | ||
** L19 leader: ''[[rplS]]'' | ** L19 leader: ''[[rplS]]'' | ||
| − | |||
** [http://rfam.sanger.ac.uk/family?acc=RF00559 L21_leader]:in front of the ''[[rplU]]-[[ysxB]]-[[rpmA]]'' operon | ** [http://rfam.sanger.ac.uk/family?acc=RF00559 L21_leader]:in front of the ''[[rplU]]-[[ysxB]]-[[rpmA]]'' operon | ||
Revision as of 19:58, 17 December 2009
RNA switches are regulatory systems that rely on alternative mRNA structures.
RNA switches may be triggered by proteins, tRNAs (T-box), or metabolites (riboswitches)
List of Bacillus subtilis RNAswitches
- Protein-dependent RNA switches
- Potential additional RNA switches
The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.
- ydaO-yuaA switch: ydaO, ktrA
- ykkC-yxkD switch: ykkC, yxkD
- yybP-ykoY switch: yybP, ykoY
- ylbH switch: ylbH
- L10 leader: rplJ
- L13 leader: rplM
- L19 leader: rplS
- L21_leader:in front of the rplU-ysxB-rpmA operon
Important Reviews
Michael D Dambach, Wade C Winkler
Expanding roles for metabolite-sensing regulatory RNAs.
Curr Opin Microbiol: 2009, 12(2);161-9
[PubMed:19250859]
[WorldCat.org]
[DOI]
(I p)
Tina M Henkin
Riboswitch RNAs: using RNA to sense cellular metabolism.
Genes Dev: 2008, 22(24);3383-90
[PubMed:19141470]
[WorldCat.org]
[DOI]
(P p)
Jesse C Cochrane, Scott A Strobel
Riboswitch effectors as protein enzyme cofactors.
RNA: 2008, 14(6);993-1002
[PubMed:18430893]
[WorldCat.org]
[DOI]
(I p)
Catherine A Wakeman, Wade C Winkler, Charles E Dann
Structural features of metabolite-sensing riboswitches.
Trends Biochem Sci: 2007, 32(9);415-24
[PubMed:17764952]
[WorldCat.org]
[DOI]
(P p)
Irnov, A Kertsburg, W C Winkler
Genetic control by cis-acting regulatory RNAs in Bacillus subtilis: general principles and prospects for discovery.
Cold Spring Harb Symp Quant Biol: 2006, 71;239-49
[PubMed:17381303]
[WorldCat.org]
[DOI]
(P p)
Frank J Grundy, Tina M Henkin
From ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangements.
Crit Rev Biochem Mol Biol: 2006, 41(6);329-38
[PubMed:17092822]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler
Riboswitches and the role of noncoding RNAs in bacterial metabolic control.
Curr Opin Chem Biol: 2005, 9(6);594-602
[PubMed:16226486]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler, Ronald R Breaker
Regulation of bacterial gene expression by riboswitches.
Annu Rev Microbiol: 2005, 59;487-517
[PubMed:16153177]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler
Metabolic monitoring by bacterial mRNAs.
Arch Microbiol: 2005, 183(3);151-9
[PubMed:15750802]
[WorldCat.org]
[DOI]
(P p)
Frank J Grundy, Tina M Henkin
Regulation of gene expression by effectors that bind to RNA.
Curr Opin Microbiol: 2004, 7(2);126-31
[PubMed:15063848]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler, Ronald R Breaker
Genetic control by metabolite-binding riboswitches.
Chembiochem: 2003, 4(10);1024-32
[PubMed:14523920]
[WorldCat.org]
[DOI]
(P p)
