RNA degradosome

Components of the RNA degradosome

• RNase Y: ssRNA endonuclease
• RNase J1: 5'-3' exonuclease, does also have endonuclease activity
• polynucleotide phosphorylase: 3'-5' exonuclease
• RNase J2: ssRNA endonuclease, may also have exonuclease activity
• CshA
• enolase
• phosphofructokinase

Related pages

• RNases
• DEAD-box RNA helicases

Reviews on the B. subtilis RNA degradosome

Sylvain Durand, Ciaran Condon
RNases and Helicases in Gram-Positive Bacteria.
Microbiol Spectr: 2018, 6(2);
[PubMed:29651979] [WorldCat.org] [DOI] (I p)

Martin Lehnik-Habrink, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, Christina Herzberg, Jörg Stülke
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Mol Microbiol: 2011, 81(6);1459-73
[PubMed:21815947] [WorldCat.org] [DOI] (I p)

Original publications on the B. subtilis RNA degradosome

Nora Cascante-Estepa, Katrin Gunka, Jörg Stülke
##Title##
Front Microbiol: 2016, 7;1492
[PubMed:27708634] [WorldCat.org] [DOI] (P e)

Martin Lehnik-Habrink, Henrike Pförtner, Leonie Rempeters, Nico Pietack, Christina Herzberg, Jörg Stülke
The RNA degradosome in Bacillus subtilis: identification of CshA as the major RNA helicase in the multiprotein complex.
Mol Microbiol: 2010, 77(4);958-71
[PubMed:20572937] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632] [WorldCat.org] [DOI] (I p)