Difference between revisions of "QdoR"

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(Expression and regulation)
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* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:'''
+
** induced by flavonoids such as quercetin ([[YxaF]], [[LmrA]]) {{PubMed|17483215}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** subject to autorepression {{PubMed|17483215}}  
+
** [[LmrA]]: transcription repression {{PubMed|15317768}}
** [[LmrA]]: transcription repression {{PubMed|17483215}}
+
** [[YxaF]]: transcription repression {{PubMed|17483215}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 18:19, 13 February 2010

Gene name yxaF
Synonyms
Essential no
Product transcriptional regulator
Function control of quercetin utilization
MW, pI 20 kDa, 6.111
Gene length, protein length 573 bp, 191 aa
Immediate neighbours qdoI, yxnA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxaF context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU39990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): LmrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: flavonoids such as quercetin act as molecular inducers and result in release from DNA targets PubMed
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kazutake Hirooka, Satoshi Kunikane, Hiroshi Matsuoka, Ken-Ichi Yoshida, Kanako Kumamoto, Shigeo Tojo, Yasutaro Fujita
Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in response to flavonoids.
J Bacteriol: 2007, 189(14);5170-82
[PubMed:17483215] [WorldCat.org] [DOI] (P p)

Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760] [WorldCat.org] [DOI] (P p)