pyrP

168

uracil permease

locus: BSU_15480

Molecular weight: 45.41 kDa

pI: 9.5

Protein length: 435 aa

Gene length: 1308 bp

function: uracil transport in/out via proton symport

product: uracil permease

essential: no

synonyms: pyrP

List of homologs in different organisms, belongs to COG2233 (Galperin et al., 2021)

Gene

Coordinates: 1,619,023  1,620,330

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The protein

Protein family

• [wiki|xanthine/uracil permease family] (according to UniProt)
• [wiki|Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily] (according to UniProt)

Structure

• [PDB|3QE7] (E. coli uracil transporter, 43% identity) [pubmed|21423164]
• [AF|P39766]

[wiki|Localization]

• cell membrane [Pubmed|18763711]

Biological materials

Mutant

• BKE15480 ([gene|A5C26E10085868A0A193C450DF58D54C636B7C2D|pyrP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGATGATTTCCCCCTGAT,  downstream forward: _UP4_ACATCTGAACAACATCATAT
• BKK15480 ([gene|A5C26E10085868A0A193C450DF58D54C636B7C2D|pyrP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGATGATTTCCCCCTGAT,  downstream forward: _UP4_ACATCTGAACAACATCATAT
• BP1258 ([gene|A5C26E10085868A0A193C450DF58D54C636B7C2D|pyrP]::cat trp+) available in [wiki|Jörg Stülke]'s & [wiki|Fabian Commichau]'s lab

References

• 7868607,8206849,12896995,16133632,1709162,17322189,18763711,21423164