pyrH

168

uridylate kinase

locus: BSU_16510

Molecular weight: 25.93 kDa

pI: 5.1

Protein length: 240 aa

Gene length: 723 bp

function: pyrimidine biosynthesis

product: uridylate kinase

essential: yes

ec: 2.7.4.22

synonyms: pyrH, smbA

List of homologs in different organisms, belongs to COG0528 (Galperin et al., 2021)

Gene

Coordinates: 1,719,802  1,720,524

Phenotypes of a mutant

• essential [Pubmed|28189581]

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The protein

Catalyzed reaction/ biological activity

• ATP + UMP --> ADP + UDP (according to UniProt)

Protein family

• UMP kinase family (single member, according to UniProt)

Structure

• [PDB|2JJX] (from ''Bacillus anthracis'', 42% identity, 64% similarity) [Pubmed|18625239]
• [AF|O31749]

[wiki|Localization]

• cytoplasm (according to Swiss-Prot)

References

• 12869195,8206849,1709162,28189581