pyrF
168
orotidine 5-phosphate decarboxylase
locus
BSU_15550
Molecular weight
25.84 kDa
pI
5.84
function
pyrimidine biosynthesis
product
orotidine-5-phosphate decarboxylase
essential
no
ec
4.1.1.23
synonyms
pyrF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0284 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,628,622 1,629,341
Phenotypes of a mutant
poor growth [pubmed|28189581]
non-transformable [pubmed|28189581]
The protein
Catalyzed reaction/ biological activity
H+ + orotidine 5'-phosphate --> CO2 + UMP (according to UniProt)
Protein family
OMP decarboxylase family (single member, according to UniProt)
Structure
[PDB|1DBT]
[AF|P25971]
Biological materials
Mutant
BKE15550 ([gene|5D0D0D2413377FCA92440334E92B5A27A5963D9E|pyrF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAGTGTTTCTTCAGCTGACG, downstream forward: _UP4_GCCTATAAGGCTGTCAGACT
BKK15550 ([gene|5D0D0D2413377FCA92440334E92B5A27A5963D9E|pyrF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAGTGTTTCTTCAGCTGACG, downstream forward: _UP4_GCCTATAAGGCTGTCAGACT
References
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Time of last update: 2024-04-24 09:56:15
Author of last update: Melvin.boenninger