Difference between revisions of "PyrE"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU15560
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P25972 P25972]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P25972 P25972]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15560 BSU15560]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15560]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.4.2.10 2.4.2.10]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.4.2.10 2.4.2.10]

Revision as of 12:00, 3 June 2009

  • Description: orotate phosphoribosyltransferase

Gene name pyrE
Synonyms pyrX
Essential no
Product orotate phosphoribosyltransferase
Function pyrimidine biosynthesis
MW, pI 23 kDa, 5.631
Gene length, protein length 648 bp, 216 aa
Immediate neighbours pyrF, cysH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PyrE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15560

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  • Protein family: PyrE subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed