PyrC

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  • Description: dihydroorotase

Gene name pyrC
Synonyms
Essential no
Product dihydroorotase
Function pyrimidine biosynthesis
MW, pI 46 kDa, 5.427
Gene length, protein length 1284 bp, 428 aa
Immediate neighbours pyrB, pyrAA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PyrC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate (according to Swiss-Prot)
  • Protein family: Type 2 subfamily (according to Swiss-Prot)
  • Paralogous protein(s): PucH

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed