Difference between revisions of "PyrB"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15490&redirect=T BSU15490] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pyrRPBCAAABKDFE.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pyrRPBCAAABKDFE.html] | ||
| Line 96: | Line 97: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15490&redirect=T BSU15490] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3R7D 3R7D] {{PubMed|21663747}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3R7D 3R7D] {{PubMed|21663747}} | ||
Revision as of 13:40, 2 April 2014
- Description: aspartate carbamoyltransferase
| Gene name | pyrB |
| Synonyms | |
| Essential | no |
| Product | aspartate carbamoyltransferase |
| Function | pyrimidine biosynthesis |
| Gene expression levels in SubtiExpress: pyrB | |
| Metabolic function and regulation of this protein in SubtiPathways: pyrB | |
| MW, pI | 34 kDa, 5.341 |
| Gene length, protein length | 912 bp, 304 aa |
| Immediate neighbours | pyrP, pyrC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15490
Phenotypes of a mutant
Database entries
- BsubCyc: BSU15490
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate (according to Swiss-Prot)
- Protein family: ATCase/OTCase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-303 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU15490
- UniProt: P05654
- KEGG entry: [3]
- E.C. number: 2.1.3.2
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulatory mechanism:
- PyrR: RNA switch, transcription termination/ antitermination (in the presence of uridine nucleotides: termination, in their absence: antitermination) PubMed
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
