PyrAA

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  • Description: carbamoyl-phosphate synthetase (glutaminase subunit)

Gene name pyrAA
Synonyms
Essential no
Product carbamoyl-phosphate synthetase (glutaminase subunit)
Function pyrimidine biosynthesis
MW, pI 39 kDa, 5.818
Gene length, protein length 1092 bp, 364 aa
Immediate neighbours pyrC, pyrAB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PyrAA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate (according to Swiss-Prot)
  • Protein family: carA family (according to Swiss-Prot)
  • Paralogous protein(s): CarA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed