Difference between revisions of "PurS"

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|style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.594   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.594   

Revision as of 11:01, 11 June 2009

  • Description: phosphoribosylformylglycinamidine synthase

Gene name purS
Synonyms yexA
Essential no
Product phosphoribosylformylglycinamidine synthase
Function purine biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 9 kDa, 4.594
Gene length, protein length 252 bp, 84 aa
Immediate neighbours purC, purQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PurS context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU06460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0062 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of adenine or adenosine(PurR) PubMed
    • repressed in the presence of guanine(G-box) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed